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Authors
Affiliations
1 Department of Physiology, S.R.M. Medical College Hospital and Research Centre, Potheri (T.N.), IN
2 Department of Physiology, SRM Medical College Hospital and Research Centre, Potheri (T.N.), IN
Source
International Journal of Medical Sciences, Vol 4, No 1-2 (2011), Pagination: 13-17
Abstract
Sub clinical hemochromatosis has been considered as one of the probable cause for diabetes mellitus and this fact gave us an impetus to study the serum ferritin level in type 2 diabetes mellitus and correlate with HbA1c and MBG. This study was conducted in forty seven diabetic patients and compared with forty seven normal age-matched individuals as the control group. Blood samples had been taken from the subject after overnight fasting; the serum ferritin levels, HbA1C and mean blood glucose level were measured. Data were analyzed by student "t" test, chi- square analysis, and correlation coefficient test. Serum ferritin, HbA1c and MBG were significantly increased in type 2 diabetes patients. Out of the forty seven diabetic patients twenty four had hyperferritinemia, and twenty eight cases had poor control of HbA1c and MBG level. From this study it was concluded that 51 per cent of the diabetes patients had significantly higher serum ferritin level when compared to the normal and there is no correlation between serum ferritin, HbA1c and MBG but there is a positive correlation between HbA1c and MBG. Thus elevated serum ferritin concentration was associated with an increased risk of diabetes.
Keywords
Diabetes Mellitus, Serum Ferritin, Glycated Hemoglobin, Mean Blood Glucose Level, Hemochromatosis.
